edit: Wait, just so I'm clear, the number of registers you HAVE or the ones you USE? Every day once registers are banked and cash office is complete there should be start funds in every register and start funds prepared FOR every register in the safe. The start funds don't change based on how many registers you use, that's always the same, it's based on how many you have. If that's what you meant then ignore everything below this.
Hahaaaaaa yeah the advances should change depending on how many registers. I don't know how universal bag numbers or SCWs are but for my store, the first cash advance column is 015 (regular change fund cash) and the start funds for every non-SCO register. So we have nine checklanes, two electronics, and two pharmacy that all take one type of SF, and four GS registers that take another. That plus 015 cash is the first column. Second column is 016 (SCO fund) plus 4 SCO advances. Then the first column on the bottom is coin change fund.
... It's been like six months since I had to do all this math a million times as we finally solidified our number of registers post-remodel, but I think I'm right. I'm kind of surprised that the Sales Audit people haven't contacted your store, but I also kind of think they don't really care as long as the safe balances out.